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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecbc80bd8db8f4677ef1c499417f9451704777dd5243e98f7b4d05cb1f5c032' 
  AND token = '2V/mlX4y/KCogGCnl9tm5wxVedk6Zm5iqemktTYeDD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}