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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b04f0dbbfee75052823d179ec7fe80388db79314a24b9fd708f4d38450cdad' 
  AND token = 'ykVO3poeNRsdJh2bBR7YqsQUhVUj+tDKaL7hkKl7aec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}