SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16407de2f0d78172f7eafc1e877c8595f72be3ecf53c3a12bbe0d4388a4d8f56' 
  AND token = 'MkVwoTFHperq8d5gyTJp4ONBl+xdSkYzwScLMh2+hoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}