SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0db6a8da126a1772b3a8beb5a3ea47f3f35dee12305bc0877bee21430b6a3235' 
  AND token = 'lFgX7v9y8iELXfh1vZUc1NfrSCtpVh4LMDkZyjp3v6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}