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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2cd900fc4303b15d0edde2b2a15a1696d7626e115541eb80004edb421979b61' 
  AND token = 'PAPQABMvoqgBaTKwWTQEnVBxqu2D8zFnkwgQ+gtSEao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}