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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a78d114f4c344e4b6d6354a684003a36915771c0d83fc69c1b09aac1bcc1547' 
  AND token = '2uSueXkH3AfDXBGKbVLm2VbCpVs8vFWjRqPip5d870U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}