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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d49bbc3c1b042727b63c7448261f5762bde25237e67cbf35a78cdd4630555f6' 
  AND token = 'w1Ux6dCAGcIrFZ3WVLerS3O0vbMFGB7pwaWyRXCpOYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}