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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8497c9bea5d72398bfa3cdd27e00946b62671991e67f19534e3e1963c20b4fc' 
  AND token = 'cMvjRU6+mcw5U4QmLfgFdCIy0AMSIqCei9iiQHRYc2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}