SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9fc8b2d6d02db2befb0d609b57128d0856ab5b0b39a0ec1b9d2e6809b65249' 
  AND token = 'nlKx4WCF5czSBlMvTf4fvOarEYf86PzgIgW9AjFCdzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}