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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20888e692b1280c72c7d279af1e3517360d53b7c0480798e49e7792183b1aa53' 
  AND token = 'zxRNzzNNAYZWGh+Y8hdLcMCPPWRl8nVoh4mc328z7vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}