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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f2621a4a0d042e10a0e43fab2251808b7a2179028acb5764d43458ccaa7ee7' 
  AND token = 'X+FJQfFzcKkob2yDDpuQk4D8KXSza/ahGPM+e6DCmiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}