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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4ce1294b051c376056842666544afcd5acbfb33db91a21fe7da1212f06dbcb' 
  AND token = '/Kh1P7uFJ4Wo7OiRf2POXGyKWwn1RziGuJdzxREsrYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}