SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f270fdf5f4f320f07ca313c4257ac63655c28be353827a865e8ac10bdea0a377' 
  AND token = 'mEnSVwUvRMWfHDHKSq+NDcz7oXgvCYrzCY4hX1nAo18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}