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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fd871ab6bc1215793dd61f706f136a5360c9d19b0edad5727ad446ce4a436c' 
  AND token = 'NnMsAK3fgKuuvDWgrFVLIHR08BTeMw+Lpz0NBlnDQso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}