SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d99a4d6d4bd743b9f1e7b8e08e7dad378d950513794408aa2ff08ae951bb512' 
  AND token = '9S1/Y/KESJIBVA7OuA+DZeOMR4flUr8BgYxuP+v8InA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}