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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a269676a41bfa5c94bd90ab80475def13ae1ed13c0006767a1e7cb98c4cf8e' 
  AND token = 'E8mMz1hXsxY4zXKTCWGbkWMF+ioqsmsMQoI2UKwU45U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}