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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185e6614c5d9d81e3b40d0450b7c41f99d0b708b340824c1ffd97321579d88fb' 
  AND token = 'TsleTwYl5i9tL1/b/OJdJVlPOgxQ9exdwFIHqQHDvHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}