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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921a25736fe2f9c0644a4d822b123cfae018b61622cc9a8c66cc3f78f947f4a3' 
  AND token = 'UitNFMn/UyK0s3s6NQ/k0e3dIqpLfm0fN5aniQr6epo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}