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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c83a29fe35704f1988571c4ee8a366e06d01f0075582028559165af551e87e9' 
  AND token = 'D7Gl9/AsNtzvat+hoeR573pdN2wIy9mNn/GFRaU0Ij8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}