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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a2be0e9805de3c77f8947d8cfa449efa363410198a57db7457b7f94e0d5b96' 
  AND token = 'HsPZ7eLLu4rjdDUmQIs+JTiEcB8Wx9ibrprZF4W4xaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}