SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da7188fa87f7f0d5008d40bab04cb906ccf152734563bb99f5f7331a013a79b' 
  AND token = 'f+fEfsxMPuIENiVM5PI3NBiUl4HD3SZyicI6JH9jqr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}