SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52743ab59074301a9cc0a33762cb9620ee889d6eaa102b04ea85df151bc7303b' 
  AND token = 'jTunFEY9tSSq41DhL7+3vu3Yw6Wp/OMVF3rVBFXtPtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}