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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b59216c9bd4be0d9eedf9a81645e44ee81e98d1bb2b6a1867f455c1445aa9af' 
  AND token = 'yOEA/eZWa6J5Wpzjp+LyMLAYwRojjY7SHBG8EVj8VtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}