SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d41ba31a7e8ee5e05922e2f64e8b59b30891d9a1b6d20d6809d935337a0a4a6' 
  AND token = 'n1ILNelUKy7V9aLhxiLedCVcvfzBNK3y+4zb9MNTgfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}