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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265c007ada08e5b0256a3d1e22321e4a775148dfb1aaec4c7dbe1def970d16a2' 
  AND token = 'CXDvOAycsi1l7jOY9ZbnQTCcpji7oK4KsEO+a+LDidE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}