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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfdc6412b143e620975a9c8a9faa1638a0d23c7bafbe8ff0742163272b4b1a2f' 
  AND token = 'l2uK59kHWLxfSMcPAWMjHrnUf7PSg1YkXPZKuP+k0Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}