SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee22fca62c37b7853752392bac7314f896b3979e70dd3c1d14a06e3c945fa020' 
  AND token = 'RhOCq3qW+nZI8+zQXrm0Ue3kwRQIPVh8vvo5uGBE54w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}