SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4557b51d8c4e0869526d928f634e70269f37ad3fe000f6e20b85e5235e740a28' 
  AND token = '3wjUtHAiIb61tuGuliWuCtMMrFQ1+TUQ0AB+d1RV2cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}