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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a9a69a60027bbecad69bef65cdc1ab201cab0ed3372153b7cba66caf68a4ef' 
  AND token = 'P4OAqKDj9amwhjS3naop9rNTlqHOsA1f7nC/R47//Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}