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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bc1e2a232e530d37061e1cb0b73ffa7d9bbca47d1d287845745f60464fc13a' 
  AND token = 'NiIWYEg/7hdk/rk2fs3cfeUR14MAP9JP5qIfwrzj4o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}