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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9133d3030425ce4432326e595d74c62186726874d13e2e7b66950b1ff5aac77' 
  AND token = 'MAUCajlauwKFtVA4/ys0dLOdAg7d6KL8WSC4fKU1ad8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}