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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60a4e50aece845ad36121600c6e4264cf581bb220e8148d1f92ce4f9d7a89ac3' 
  AND token = 'nBXtJvF6/9Ms//+E1iK0trwJxK5G8SUAfBs/ZFkT0qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}