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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901cf6aaa593ce2c3f14f89107bff04ae79192882c3a126a11b3c635a65a22a0' 
  AND token = 'PuMO2cWWgAShEGnBXzzQzELsUN/qFKW2e7Yp6g/mG5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}