SELECT 
  product_id, 
  feature_id, 
  variant_id 
FROM 
  cscart_product_features_values 
WHERE 
  product_id IN (269817, 270047, 270048, 270049) 
  AND feature_id IN (880, 922, 925) 
  AND lang_code = 'en'

Query time 0.00200

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "5.84"
    },
    "table": {
      "table_name": "cscart_product_features_values",
      "access_type": "range",
      "possible_keys": [
        "PRIMARY",
        "fl",
        "lang_code",
        "product_id",
        "fpl",
        "idx_product_feature_variant_id"
      ],
      "key": "lang_code",
      "used_key_parts": [
        "lang_code",
        "feature_id",
        "product_id"
      ],
      "key_length": "12",
      "rows_examined_per_scan": 12,
      "rows_produced_per_join": 12,
      "filtered": "100.00",
      "using_index": true,
      "cost_info": {
        "read_cost": "3.44",
        "eval_cost": "2.40",
        "prefix_cost": "5.84",
        "data_read_per_join": "9K"
      },
      "used_columns": [
        "feature_id",
        "product_id",
        "variant_id",
        "lang_code"
      ],
      "attached_condition": "((`webmarco`.`cscart_product_features_values`.`product_id` in (269817,270047,270048,270049)) and (`webmarco`.`cscart_product_features_values`.`feature_id` in (880,922,925)) and (`webmarco`.`cscart_product_features_values`.`lang_code` = 'en'))"
    }
  }
}

Result

product_id feature_id variant_id
269817 880 60248
270047 880 60248
270048 880 60248
270049 880 60248
269817 922 64114
270047 922 64115
270048 922 64116
270049 922 64117
269817 925 62784
270047 925 62784
270048 925 62784
270049 925 62784