SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eddb7f7911311635734080175ed205a6b790930e52793d8b3fcf55c8fcb11cdf' 
  AND token = 'S35gK87lXWovu4Aazmt3ZhjBoIIZR2aWcLY0uPxkCQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}