SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea52fc0a16dae9c41f6d38f88664f81379a7f14a1ebb44259b49882b081882fb' 
  AND token = 'VxNZ/+aMM47whmaRUFYl7VHRok0Y5IjDqO4oFuFwV7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}