SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0bc677c2ad552d7858dfa8b33d73de1c20c53356d48ce8af865f0bbdb54e377' 
  AND token = '4i+hNnS9NTbTJPQkcAIK2MZzsguvldrSzEWxdmrVffM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}