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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22dac431ed50adda4e90257ccd10ef5f2254f693755a30886c2aa848ce99628e' 
  AND token = '2YRpHcMFwB/0FKb2J3+jAlZ4LvaZIl82JHyJygvNtkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}