SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7675c904ed961923f43bdbabad7e28d4a24381d98c9d45c1e610679bd6a47e00' 
  AND token = 'lQOM1jUKrDQVnvKNPbzoeqUAO2v1vh/4RQlIWgrigJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}