SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3fb7158d2eff5b1bc282f10fb019e57e021ee0c3b0e3232d6190e070eb56cf0' 
  AND token = 'Jd7fhT/48NsG5R7KlE468TlSxjKstqpOEp/sb3g3+Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}