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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04557a0ebaf25fb3a6335dc48ba4e7e17fbb253500095d7dbe9b0ffa7f213501' 
  AND token = 'nE4El+MRHOJJuR9dq2oM6MZHMsGiApKSP3kUsEvS3Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}