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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5adc33ce3e1c5027d7a6f401b50eb60da40abf7eab3f0c5cb4f47218e00742' 
  AND token = 'FUJDCmAuiaLikNy35Mik4S7gvAUzaGue6Vix3/pgZ1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}