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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caece4bfe204f9853f9f8fa9c0dfb028cc22fbff9d549d96cec05334cff6d88' 
  AND token = 'ts9hqxw9Ctjvo1EcEv8LLMOQvEBFLjEcLJu21uZrD8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}