SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c9c2de935c7abea8bf7b9fdf9f9c19d24bbbcd04a6ad6ff4cda1afb338c338' 
  AND token = 'VxDV/0RhmMuz5Bqy/WcrT/dXMiAtu7veRyR/DAVEsLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}