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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148bd6d739102cb63a7374bd3141e5d20d5f60cf9e253307d6ad2af549bb5653' 
  AND token = 'Qy3hDnmXr8SYVkNqqd7LrBu0mkzxuzDABr9JJ846UfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}