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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1861b377e2fa8718c33b138364339d40320ccf96d72de4bda0986831024e7e01' 
  AND token = '82ZGWLeQf8YvytTYa8qfFh6lVMyKhrtC48dAAe+bmLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}