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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be78ec46824d05260d14e16d36605f289e3774c01bca5f5de60476bf722b1b95' 
  AND token = 'as3zXlADnDt3nE0Alc3LexI9tsMDy4yUyrM9O+tvJyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}