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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce72a0fa50681f1008b5b74b16df0a58878c941a3da200bd8db1c3b168d82899' 
  AND token = '1AV8ZIcory7cTP0GxKJlfVEulpi2rUdujNZOClgdZZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}