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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4630ba6d6e6248fcc79d2293c1ab73378c1baf78a1b0485e312fc7afe180c80' 
  AND token = '/FBIArYaLHlQvchyW11Lk8WMyH7D/dXQ+Yuw/kbVf2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}