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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f091c8da47c7483e8cdfbf543d62d3f98138a5708cc0121adc9cf78f9143285' 
  AND token = 'KrZOrYe/aqI4lNRbr7GDZz8idKEth9x3wNqSXdoIChM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}